WebMay 6, 2024 · Compared with the control treatment, TNF-α exposure induced a marked reduction in TEER in the Caco-2 cell monolayer (Fig. 1).Treatment with different Lactobacillus strains exhibited varied effects on the regulation of barrier function. The degree of recovery of the TEER of strains with superior regulation ability, such as L. fermentum … WebJan 1, 2024 · Similarly, exposure of Caco-2 cells to E. coli reduced the mRNA expression of key tight junction genes, viz. Zo-1, Claudin-1, Occludin and Cingulin which however were restored significantly (p < 0 ...
Outer Membrane Vesicles and Soluble Factors Released by Probiotic ...
WebFeb 14, 2024 · The biological effect of proteolysis of gliadin by probiotic bacteria was analyzed in relation to intestinal permeability, inflammation or oxidative stress on the intestinal cells. Our results clearly show that the PT fragments from gliadin are able to induce tight junction destabilization and an inflammatory state on intestinal Caco-2 cells. WebAug 22, 2024 · In healthy individuals, tight junction proteins (TJPs) maintain the integrity of the intestinal barrier. Dysbiosis and increased intestinal permeability are observed in … fruit of the season
Polyphenols Protect the Epithelial Barrier Function of Caco-2 Cells ...
WebMay 25, 2024 · 4.4. Effects of Three Common Probiotics on Caco-2 Cytoskeleton. β-Tubulin (β-tubulin) is an important component of cytoskeleton.After being treated with 10 8 CFU/ml Lactobacillus bulgaricus, Lactobacillus acidophilus, and Streptococcus thermophilus for 24 hours, the β-tubulin of Caco-2 cells was labeled by immunofluorescence method, … WebMar 17, 2024 · Tight junctions (TJs) play an important role in intestinal barrier function. ... Much more information is available on the effect of commensal and probiotic bacteria on the regulation of the intestinal barrier. ... The pentapeptide NPWDQ derived from bovine α s-2 casein reinforces the barrier integrity of intestinal Caco-2 cells, leading to ... fruit is or fruit are